HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl 2-phosphonopropionate → 2-Phosphonopropionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl 2-phosphonopropionate | HCID 107155 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 2-Phosphonopropionic acid | HCID 73187 | — |
Reaction Steps
A mixture of ethyl-2-(diethoxyphosphinyl)propionate (15 g., 0.063 moles) in 6 N hydrochloric acid (150 ml.) is heated to reflux for 2.5 hours. After this time, the reaction vessel is fitted with a Dean-Stark trap and heated at reflux an additional thirty minutes. The reaction mixture is concentrated in vacuo to yield 2-phosphonopropionic acid (quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151172 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-51634a379c774f2fb0c7ff187d1ea7c9 |
| Source note | uspto-grants-1979_04 |