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Alternatively, a mixture of 2-nitroimidazole, anhydrous potassium carbonate, and (S)-(+)-epichlorohydrin is refluxed for 10 minutes then filtered while hot. The filtrate is concentrated and cooled to give a solid. Crystallization from ethanol and further processing gives the product.

1. temperatureis refluxed for 10 minutes
2. filtrationthen filtered while hot
3. concentrationThe filtrate is concentrated
4. temperaturecooled
5. customto give a solid
6. customCrystallization from ethanol and further processing
7. customgives the product