HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → HCID 19031177, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 1-(piperidin-4-yl)-3,4-dihydroquinolin-2(1H)-one | HCID 10728185 | — |
| Product | HCID 19031177 | HCID 19031177 | — |
Reaction Steps
1-(4-Piperidinyl)-3,4-dihydrocarbostyril (0.2 g) is added to conc. sulfuric acid (5 ml) and thereto is added fuming nitric acid (0.1 ml) under ice cooling. The mixture is stirred at room temperature for 30 minutes, and then the reaction mixture is poured into ice-water. The mixture is basified and extracted with dichloromethane. The solvent is concentrated to give 6-nitro-1-(4-piperidinyl)-3,4-dihydrocarbostyril (0.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05652247 |
| Source dataset | uspto-grants-1997_07 |
| ORD ID | ord-d309b23a920641b49a78afab88e472f8 |
| Source note | uspto-grants-1997_07 |