HRID266896

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15187049

3,4-Dihydrospiro[2H-1-benzopyran-2,4′-piperidine]

C13H17NO

结构：CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O

HCID15895387

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC2(CCc3ccccc3O2)CC1

HCID22862460

未命名化合物

PROCEDURE

实验过程

This intermediate was prepared from the product of Step A and α(R)-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-2,2-dimethyl-1-oxoethyl]amino]-1H-indole-3-propanoic acid following standard peptide coupling methods.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fc133c2011e44a9990c77440d620e31c
来源数据集: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05652235
来源说明: uspto-grants-1997_07

反应 SMILES

[NH:1]1[CH2:6][CH2:5][C:4]2([CH2:11][CH2:10][C:9]3[CH:12]=[CH:13][CH:14]=[CH:15][C:8]=3[O:7]2)[CH2:3][CH2:2]1.[CH3:16][C:17]([CH3:43])([O:19][C:20]([NH:22][C:23]([CH3:42])([CH3:41])[C:24]([NH:26][C@H:27]([CH2:31][C:32]1[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[NH:34][CH:33]=1)[C:28](O)=[O:29])=[O:25])=[O:21])[CH3:18]>>[N:1]1([C:28]([C@H:27]([NH:26][C:24](=[O:25])[C:23]([NH:22][C:20]([O:19][C:17]([CH3:43])([CH3:18])[CH3:16])=[O:21])([CH3:42])[CH3:41])[CH2:31][C:32]2[C:40]3[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=3)[NH:34][CH:33]=2)=[O:29])[CH2:6][CH2:5][C:4]2([CH2:11][CH2:10][C:9]3[CH:12]=[CH:13][CH:14]=[CH:15][C:8]=3[O:7]2)[CH2:3][CH2:2]1