HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21322275, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-(4'-Chloro-4-biphenylyl)-6-(tetrahydropyran-2-yloxy)-3-hexyn-2-ol | HCID 21322233 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21322275 | HCID 21322275 | — |
Reaction Steps
To 38.5 g. of 2-(4'-chloro-4-biphenylyl)-6-(tetrahydropyran-2-yloxy)-3-hexyn-2-ol in 250 ml. of dioxane, is added dropwise with ice cooling, 100 ml. of 1 N HCl. The resulting mixture is stirred 12 hours more at 0°. After the usual work up, 2-(4'-chloro-4-biphenylyl)-3-hexyn-2,6-diol, m.p. 105°, is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151294 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-c7073d8bbe4545fc9e2263142e00b903 |
| Source note | uspto-grants-1979_04 |