4-Chlorobenzoic Acid → HCID 178432736, compound

HRID 267202Notes

Reaction equation

HRID 267202 reaction equation
[NH2:1][C:2]1[NH:7][CH2:6][C:5]2=[C:8]([CH3:15])[N:9]=[C:10]([CH2:11][CH:12]([CH3:14])[CH3:13])[N:4]2[N:3]=1.[CH:16]1[C:21]([C:22](O)=[O:23])=[CH:20][CH:19]=[C:18]([Cl:25])[CH:17]=1>>[CH3:15][C:8]1[N:9]=[C:10]([CH2:11][CH:12]([CH3:13])[CH3:14])[N:4]2[C:5]=1[CH2:6][NH:7][C:2]([NH:1][C:22](=[O:23])[C:21]1[CH:20]=[CH:19][C:18]([Cl:25])=[CH:17][CH:16]=1)=[N:3]2

Participants

3

Reactant 2

HCID 63184-Chlorobenzoic AcidHCID 178432737HCID 178432737, compound

Product 1

HCID 178432736HCID 178432736, compound

Procedure

N-(3,4-Dihydro-5-methyl-7-isobutylimidazo[ 5,1-f]-as-triazin-2-yl)-p-chlorobenzamide, m.p. 236°-239° was prepared from 2-amino-3,4-dihydro-5-methyl-7-isobutylimidazo[5,1-f]-as-triazine (Example 1d) and P-chlorobenzoic acid. It was converted into its hydrochloride salt m.p. 240°-247°.

Sources & evidence

ORD record
ord-bf60dd12fa4947ecbbde9768827be1d7
Source dataset
uspto-grants-1976_03
Patent number
US03941785

Reaction notes

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