Formic Acid → HCID 178440031, compound

Participants

Reaction Steps

2-Amino-3,4-dihydro-5-methyl-7-propylimidazo[ 5,1-f]-as-triazine (Example 1a) (2.2 g.) in formic acid (50 ml., 99°) was heated under reflux for 24 hours and evaporated under reduced pressure. The residue was stirred with 2N sodium carbonate and the solid was collected and dried and had m.p. 188.5°-190.5°. Its hydrogen maleate salt had m.p. 159°-161° (crystallised from a mixture of methanol and ether).

Provenance & Evidence