反应详情

7-Benzoly-5-chloroindoline was prepared by treating 1-acetyl-5-chloroindoline with benzoyl chloride at 120°-175°C. using zinc chloride as a catalyst. The acetyl group was removed by acid hydrolysis to give the yellow colored 7-benzoyl-5-chloroindoline. The yellow solid melted at 112°-115°C. A mixture melting point with material prepared in Example 2 showed no depression.

1. customThe acetyl group was removed by acid hydrolysis