HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → 7-Benzoyl-5-chloroindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 1-Acetyl-5-chloroindoline | HCID 12321990 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Product | 7-Benzoyl-5-chloroindoline | HCID 21555979 | — |
Reaction Steps
7-Benzoly-5-chloroindoline was prepared by treating 1-acetyl-5-chloroindoline with benzoyl chloride at 120°-175°C. using zinc chloride as a catalyst. The acetyl group was removed by acid hydrolysis to give the yellow colored 7-benzoyl-5-chloroindoline. The yellow solid melted at 112°-115°C. A mixture melting point with material prepared in Example 2 showed no depression.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03941806 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-531f90d49513458c87122e7c294768fe |
| Source note | uspto-grants-1976_03 |