Hydrochloric Acid → HCID 21556724, compound

HRID 267264Notes

Reaction equation

HRID 267264 reaction equation
[CH3:1][O:2][C:3](=[O:7])[CH2:4][C:5]#[N:6].[CH2:8]([CH:10]1[O:12]C1)[Cl:9].Cl>>[ClH:9].[CH3:1][O:2][C:3]([CH2:4][C:5](=[NH:6])[O:12][CH2:10][CH2:8][Cl:9])=[O:7]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 7747Methyl cyanoacetateHCID 7835Epichlorohydrin

Product 1

HCID 21556724HCID 21556724, compoundYield 92%

Procedure

A mixture of 9.9 parts of methylcyanoacetate and 8.05 parts of epichlorohydrin was saturated with dry hydrogen chloride gas under ice-cooling and further cooled with icewater for one hour, followed by keeping in a refrigerator overnight. The resulting solid was washed with ethylether and dried to give 19.9 parts of 2-chloroethyl methoxycarbonylacetimidate hydrochloride. Yield 92% Melting point: 103 to 107°C (decomposition).

Workup

  1. temperaturecooling
  2. temperaturefurther cooled with icewater for one hour
  3. customby keeping in a refrigerator overnight
  4. washThe resulting solid was washed with ethylether
  5. customdried

Sources & evidence

ORD record
ord-6d88278e1412400186fba47fc52c059b
Source dataset
uspto-grants-1976_03
Patent number
US03941823

Reaction notes

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