Nitric Acid → HCID 178512759, compound

HRID 267320Notes

Reaction equation

HRID 267320 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=O.[N+:11]([O-:14])([OH:13])=[O:12].[NH2:15][NH:16][C:17]([NH:19][NH2:20])=[NH:18].[N+]([O-])(O)=O>C(O)C.O>[N+:11]([O-:14])([OH:13])=[O:12].[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=[N:15][NH:16][C:17]([NH:19][N:20]=[CH:5][C:4]1[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=1)=[NH:18]

Participants

6

Reactant 3

HCID 944Nitric AcidHCID 227103,4-DichlorobenzaldehydeHCID 178513182HCID 178513182, compound

Product 1

HCID 178512759HCID 178512759, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A boiling solution of 17.6 grams of 3,4-dichlorobenzaldehyde in 250 milliliters of ethanol is stirred vigorously as a solution of 6.1 grams of 1,3-diaminoguanidine nitrate and 0.5 milliliters of concentrated nitric acid in 50 milliliters of water is added in one portion. The reaction mixture is stirred as the temperature recedes to room temperature. The reaction mixture is then allowed to stand for several hours. The precipitate which forms is collected, washed with hot ethanol, air dried and finally dried at 60°C. under reduced pressure. The yield is 17.5 grams of product and the melting point is 195°-196°C. with decomposition.

Workup

  1. additionis added in one portion
  2. customrecedes to room temperature
  3. waitto stand for several hours
  4. customThe precipitate which forms is collected
  5. washwashed with hot ethanol, air
  6. customdried
  7. customfinally dried at 60°C. under reduced pressure

Sources & evidence

ORD record
ord-af7f828404bc46ae8dc33eb9019f6407
Source dataset
uspto-grants-1976_03
Patent number
US03941825

Reaction notes

Loading…