Diethylamine → 2'-Chloro-4-biphenylylglycolic acid, diethylammonium salt

HRID 267384Notes

Reaction equation

HRID 267384 reaction equation
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].[Cl:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][C:16]([CH:19]([OH:23])[C:20]([OH:22])=[O:21])=[CH:15][CH:14]=1>CCCCCC>[CH2:1]([NH2+:3][CH2:4][CH3:5])[CH3:2].[Cl:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][C:16]([CH:19]([OH:23])[C:20]([O-:22])=[O:21])=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 215230142'-Chloro-4-biphenylylglycolic acid

Product 1

HCID 1317100782'-Chloro-4-biphenylylglycolic acid, diethylammonium salt

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Anhydrous diethylamine (0.11 moles) is added dropwise to a stirred solution of 2'-chloro-4-biphenylylglycolic acid (0.10 moles) in 100 ml. of n-hexane at 0°C. The precipitated diethylammonium salt is collected on a filter washed with n-hexane and dried in a vacuum desiccator to obtain 2'-chloro-4-biphenylylglycolic acid, diethylammonium salt.

Workup

  1. customat 0°C
  2. customThe precipitated diethylammonium salt is collected on a filter
  3. washwashed with n-hexane
  4. customdried in a vacuum desiccator

Sources & evidence

ORD record
ord-058ea6f31877421392fb653f2581dca9
Source dataset
uspto-grants-1976_03
Patent number
US03941821

Reaction notes

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