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A mixture of 52.5 g. (0.167 moles) of ethyl α,2'-dichloro-4-biphenylylacetate and 160 ml. of glacial acetic acid containing 40 ml. of 37% hydrochloric acid is refluxed for 20 hours. The mixture is concentrated under reduced pressure to give a gummy residue. The latter material is dissolved in 300 ml. of n-hexane, washed with ice-cold water (100 ml. total), dried over sodium sulfate and filtered. The hexane is removed to give α,2'-dichloro-4-biphenylylacetic acid.

1. additionA mixture of 52.5 g
2. concentrationThe mixture is concentrated under reduced pressure
3. customto give a gummy residue
4. dissolutionThe latter material is dissolved in 300 ml
5. washof n-hexane, washed with ice-cold water (100 ml. total)
6. dry with materialdried over sodium sulfate
7. filtrationfiltered
8. customThe hexane is removed