反应详情

A mixture of 14 g. (.05 moles) of α, 2'-dichloro-4-biphenylylacetic acid and 5 g. of sodium hydrosulfide in 100 ml. of absolute ethanol and under a nitrogen atmosphere is stirred for 15 hours. The mixture is then acidified with 6 N hydrochloric acid. The solvent is removed in vacuo and the residue is extracted into ether, washed with water, saturated sodium chloride solution, dried and evaporated to dryness to obtain α-mercapto-2'-chloro-4-biphenylylacetic acid.

1. additionA mixture of 14 g
2. customThe solvent is removed in vacuo
3. extractionthe residue is extracted into ether
4. washwashed with water, saturated sodium chloride solution
5. customdried
6. customevaporated to dryness