Formaldehyde → HCID 21555847, compound

HRID 267420Notes

Reaction equation

HRID 267420 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH3:21])=[CH:19][N:18]=[CH:17]2)=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8].[CH2:22]=[O:23]>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH3:21])=[CH:19][N:18]=[C:17]2[CH2:22][OH:23])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:8]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 21497374HCID 21497374, compound

Product 1

HCID 21555847HCID 21555847, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

In the manner given in Example 1, 2.96 g. of 5-chloro-2-(5-methylimidazol-1-yl)benzophenone is heated in a bomb with paraformaldehyde in xylene to 140° C. to give 5-chloro-2-[5-methyl-2-(hydroxymethyl)imidazol-1-yl]benzophenone.

Sources & evidence

ORD record
ord-c9d05f263bfe4a07998af0f121a8cc6b
Source dataset
uspto-grants-1976_03
Patent number
US03941803

Reaction notes

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