Formaldehyde → HCID 21555840, compound

HRID 267422Notes

Reaction equation

HRID 267422 reaction equation
[F:1][C:2]([F:24])([F:23])[C:3]1[CH:4]=[CH:5][C:6]([N:17]2[C:21]([CH3:22])=[CH:20][N:19]=[CH:18]2)=[C:7]([CH:16]=1)[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:9].[CH2:25]=[O:26]>C1(C)C(C)=CC=CC=1>[F:24][C:2]([F:1])([F:23])[C:3]1[CH:4]=[CH:5][C:6]([N:17]2[C:21]([CH3:22])=[CH:20][N:19]=[C:18]2[CH2:25][OH:26])=[C:7]([CH:16]=1)[C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:9]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 21497406HCID 21497406, compound

Product 1

HCID 21555840HCID 21555840, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

In the manner given in Example 1, 5-(trifluoromethyl)-2-(5-methylimidazol-1-yl)benzophenone is heated in a bomb with paraformaldehyde in xylene to 140° C. to give 5-(trifluoromethyl)-2-[2-(hydroxymethyl)-5-methylimidazol-1-yl]benzophenone.

Sources & evidence

ORD record
ord-40cfa1cbe2e449a6b45391d957f60b66
Source dataset
uspto-grants-1976_03
Patent number
US03941803

Reaction notes

Loading…