Hydrochloric Acid → HCID 178422962, compound

HRID 267510Notes

Reaction equation

HRID 267510 reaction equation
C([O:3][CH2:4][CH2:5][N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([CH3:16])[N:14]=2)[C:9](=[O:17])[C:8]([C:18]([NH:20][C:21]2[NH:25][N:24]=[N:23][N:22]=2)=[O:19])=[CH:7]1)=O.Cl>[OH-].[Na+]>[OH:3][CH2:4][CH2:5][N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([CH3:16])[N:14]=2)[C:9](=[O:17])[C:8]([C:18]([NH:20][C:21]2[NH:25][N:24]=[N:23][N:22]=2)=[O:19])=[CH:7]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178422963HCID 178422963, compound

Product 1

HCID 178422962HCID 178422962, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

1,4-Dihydro-1(2-formyloxyethyl)-7-methyl-4-oxo-N(1H-tetrazol-5-yl)-1,8-naphthyridine-3-carboxamide (Example 4(1)) (0.5 g) in aqueous sodium hydroxide (3.5 ml), 2N) was heated on a steam bath for 10 minutes. The solution was acidified to pH 1 with a dilute hydrochloric acid and the solid was collected and dried, m.p. 315°-316° (d), (32 %).

Workup

  1. customthe solid was collected
  2. customdried

Sources & evidence

ORD record
ord-9312bc6b9d5c4288b995fed79b0ab996
Source dataset
uspto-grants-1976_03
Patent number
US03943141

Reaction notes

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