Carbon Disulfide → HCID 21454006, compound

HRID 267546Notes

Reaction equation

HRID 267546 reaction equation
[S:1]1[CH2:5][CH2:4][NH:3][CH2:2]1.[CH2:6]([N:8]([CH2:11][CH3:12])[CH2:9][CH3:10])[CH3:7].[C:13](=[S:15])=[S:14]>C(OCC)C>[S:1]1[CH2:5][CH2:4][N:3]([C:13]([S-:15])=[S:14])[CH2:2]1.[CH2:6]([NH+:8]([CH2:11][CH3:12])[CH2:9][CH3:10])[CH3:7]

Participants

5

Reactant 3

HCID 6348Carbon DisulfideHCID 8471TriethylamineHCID 10444Thiazolidine

Product 1

HCID 21454006HCID 21454006, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 70g (0.79 mole) thiazolidine** and 160g (1.58 moles) triethylamine in one liter ethyl ether was added 120g (1.58 moles) carbon disulfide at 21°-2° over a period of 30 minutes. After the mixture was stirred at ambient temperatures for an additional 2.5 hours, it was filtered to give a pale yellow solid which was then washed with 1.51. (5 × 300ml) ether to yield 201 g (96% conversion) of desired product, m.p. 101°-3°C. (gas evol.).

Workup

  1. filtrationit was filtered
  2. customto give a pale yellow solid which
  3. washwas then washed with 1.51

Sources & evidence

ORD record
ord-03e3adb2a94445a1903968118348d37b
Source dataset
uspto-grants-1976_03
Patent number
US03943143

Reaction notes

Loading…