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Water → 3-[4-(4-Carbethoxybenzenesulfonamido)benzenesulfonyl]acrylonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 反応物 | Ethyl 4-(chlorosulfonyl)benzoate | HCID 3667622 | — |
| 反応物 | 2-Cyanovinyl 4-aminophenyl sulfone | HCID 54561326 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 3-[4-(4-Carbethoxybenzenesulfonamido)benzenesulfonyl]acrylonitrile | HCID 54454498 | — |
反応手順
6.3 grams (0.03 mol) of 3-(4-aminobenzenesulfonyl)acrylonitrile are dissolved in 70 ml of acetone, and 30 ml water are added thereto. Sodium bicarbonate (2.6 g, 0.03 mol) is added with stirring, followed by a solution of 7 g (0.03 mol) of 4-carbethoxybenzenesulfonyl chloride in 30 ml acetone. The reaction mixture is stirred overnight, filtered and the filtrate diluted with 750 ml water. The dark, cream-colored solid which separates and which is recovered by filtration and drying constitutes 3-[4-(4-carbethoxyxbenzenesulfonamido)benzenesulfonyl]acrylonitrile: ##SPC31##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03943154 |
| 出典データセット | uspto-grants-1976_03 |
| ORD ID | ord-073beb967e314a39a55a9b76c4a8bff5 |
| 出典メモ | uspto-grants-1976_03 |