反应详情

6.3 grams (0.03 mol) of 3-(4-aminobenzenesulfonyl)acrylonitrile are dissolved in 70 ml of acetone, and 30 ml water are added thereto. Sodium bicarbonate (2.6 g, 0.03 mol) is added with stirring, followed by a solution of 7 g (0.03 mol) of 4-carbethoxybenzenesulfonyl chloride in 30 ml acetone. The reaction mixture is stirred overnight, filtered and the filtrate diluted with 750 ml water. The dark, cream-colored solid which separates and which is recovered by filtration and drying constitutes 3-[4-(4-carbethoxyxbenzenesulfonamido)benzenesulfonyl]acrylonitrile: ##SPC31##

1. stirringThe reaction mixture is stirred overnight
2. filtrationfiltered
3. additionthe filtrate diluted with 750 ml water
4. filtrationwhich is recovered by filtration
5. customdrying