Water → HCID 68139865, compound

HRID 267736Notes

Reaction equation

HRID 267736 reaction equation
[Cl-].[NH2:2][C:3]1[CH:8]=[C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:6]([C:16]#[N:17])=[C:5]([Cl:18])[N+:4]=1[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24].[C:25]1([SH:31])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1.C(N(CC)CC)C.O>C(O)C>[Cl-:18].[NH2:2][C:3]1[CH:8]=[C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:6]([C:16]#[N:17])=[C:5]([S:31][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[N+:4]=1[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

6

Reactant 4

HCID 962WaterHCID 7969ThiophenolHCID 8471TriethylamineHCID 12296740HCID 12296740, compound

Product 1

HCID 68139865HCID 68139865, compoundYield 51.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.7 gms (.01 ml) of 2-amino-6-chloro-5-cyano-1-n-hexyl-4-n-hexylamino pyridinium chloride (compound 11 - Table 1) was dissolved in ethanol and 1.1 gm (.01 mole) thiophenol and 1.0 gm (0.01 mole) of triethylamine added. The solution was left 16 hours at room temperature poured into iced water and 2.3 gms (50% yield) of 2-amino-5-cyano-1-n-hexyl-4-n-hexylamino-6-phenylmercapto pyridinium chloride (compound 78 - Table 5) filtered off (MPt 227° -228°C).

Sources & evidence

ORD record
ord-70e6a8b9d93f4137a260a9a45e0d8d46
Source dataset
uspto-grants-1976_03
Patent number
US03944557

Reaction notes

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