Water → HCID 21455689, compound

Participants

Reaction Steps

3.2 gms (.01 mole) of 2-amino-1-n-butyl-4-n-butylamino-6-chloro-5-cyano-pyridinium chloride (compound 6 - Table 1) was dissolved in hot water, 4.0 gms (0.04 mole) of triethylamine added and the solution refluxed on a boiling water bath. After 2 hours 2.0 gms (75% yield) of 2-amino-1-n-butyl-4-n-butylamino-5-cyano-pyridine-6-one (compound 87 - Table 6) had precipitated and was filtered off. (MPt 177° - 179°C).

Provenance & Evidence