Water → HCID 21455689, compound

HRID 267737Notes

Reaction equation

HRID 267737 reaction equation
[Cl-].[NH2:2][C:3]1[CH:8]=[C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH3:13])[C:6]([C:14]#[N:15])=[C:5](Cl)[N+:4]=1[CH2:17][CH2:18][CH2:19][CH3:20].C(N(CC)CC)C.[OH2:28]>>[NH2:2][C:3]1[N:4]([CH2:17][CH2:18][CH2:19][CH3:20])[C:5](=[O:28])[C:6]([C:14]#[N:15])=[C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH:8]=1

Participants

4

Reactant 3

HCID 962WaterHCID 8471TriethylamineHCID 12296738HCID 12296738, compound

Product 1

HCID 21455689HCID 21455689, compoundYield 75%

Procedure

3.2 gms (.01 mole) of 2-amino-1-n-butyl-4-n-butylamino-6-chloro-5-cyano-pyridinium chloride (compound 6 - Table 1) was dissolved in hot water, 4.0 gms (0.04 mole) of triethylamine added and the solution refluxed on a boiling water bath. After 2 hours 2.0 gms (75% yield) of 2-amino-1-n-butyl-4-n-butylamino-5-cyano-pyridine-6-one (compound 87 - Table 6) had precipitated and was filtered off. (MPt 177° - 179°C).

Workup

  1. temperaturethe solution refluxed on a boiling water bath

Sources & evidence

ORD record
ord-e5f460bea4dc4f82b10a87e5d6c17a2d
Source dataset
uspto-grants-1976_03
Patent number
US03944557

Reaction notes

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