HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 20528962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 20528937 | HCID 20528937 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | HCID 178493780 | HCID 178493780 | — |
| Product | HCID 20528962 | HCID 20528962 | — |
Reaction Steps
The 2-amino substituent of Step A product when treated with sodium nitrite as described in Step E of Preparation 81 is converted to the 2-hydroxy group. Treatment of the 2-hydroxy-3-morpholino-6-methoxypyrazine with phosphorus oxychloride by Preparation 13, Step B method, gives 2-chloro-3-morpholino-6-methoxypyrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946009 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-15e1aa1efc844950a563ade16aa65608 |
| Source note | uspto-grants-1976_03 |