反应详情

In a manner analogous to that described in Example 4, from 2-(3-methoxyphenoxy)-2-methylpropionic acid and ethyl 2-[4-(2-aminoethyl)-phenoxy]-2-methylpropionate, in the presence of triethylamine and ethyl chloroformate, there is obtained, in a yield of 84% of theory, ethyl 2-{{4-{2-[2-(3-methoxyphenoxy)-2-methylpropionylamino]-ethyl}-phenoxy}}-2-methylpropionate which, after recrystallization from cyclohexane and ethyl acetate, melts at 68°-69° C. and from this 2-{{4-{2-[2-(3-methoxyphenoxy)-2-methylpropionylamino]-ethyl}-phenoxy}}-2-methylpropionic acid in a yield of 64% of theory which, after recrystallization from cyclohexane and ethyl acetate, melts at 80°-81° C.