HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 21552992, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Azacyclonol | HCID 15723 | — |
| Reactant | Potassium Bicarbonate | HCID 516893 | — |
| Reactant | 6-Chloro-1-(4-methoxyphenyl)hexan-1-one | HCID 18518171 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 21552992 | HCID 21552992 | — |
Reaction Steps
A mixture of 27.6 g (0.1 mole) of α,α-diphenyl-4-piperidinemethanol, 26.5 g (0.11 mole) of 6-chloro-4'-methoxycaprophenone, 20 g of potassium bicarbonate, and 0.1 g of potassium iodide in 300 ml of toluene and 45 ml of water is stirred on a steam bath for about 82 hours then worked up by the procedure described in Example 5 to give 6-[4-(α-hydroxy-α-phenylbenzyl)piperidino]-4'-methoxycaprophenone hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946022 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-26d5cc26aa504769ba2730d44214da3f |
| Source note | uspto-grants-1976_03 |