HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanedione → HCID 70635419, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanedione | HCID 10434 | — |
| Reactant | 6-Nitroveratraldehyde | HCID 88505 | — |
| Reactant | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 70635419 | HCID 70635419 | 52% |
Reaction Steps
Boiling a solution of 8.5 g of 6-nitroveratraldehyde, 4.0 g of cyclohexane-1,3-dione and 5.2 g of amidinoacetic acid ethyl ester in 150 ml of ethanol for 1 hour yields 2-amino-4-(2-nitro-4,5-dimethoxyphenyl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 261°C (ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03946026 |
| Source dataset | uspto-grants-1976_03 |
| ORD ID | ord-d87c6629cd524435ba654ca0af3f8594 |
| Source note | uspto-grants-1976_03 |