Borane → HCID 53853643, compound

HRID 268171Notes

Reaction equation

HRID 268171 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]([CH3:12])[C:10](=[O:13])[CH:9]3[CH2:14][CH2:15][CH2:16][N:8]3[C:7](=O)[C:6]=2[CH:18]=1.B>O1CCCC1>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]([CH3:12])[C:10](=[O:13])[CH:9]3[CH2:14][CH2:15][CH2:16][N:8]3[CH2:7][C:6]=2[CH:18]=1

Participants

4

Reactant 2

HCID 6331BoraneHCID 68146862HCID 68146862, compound

Product 1

HCID 53853643HCID 53853643, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The above compound is prepared when 7-bromo-1,2,3,11 a-tetrahydro-10-methyl-5 H-pyrrolo[2,1-c] [1,4] -benzodiazepin-5,11(10H)dione (prepared by reaction of proline and 5- bromo N-methylisatoic anhydride as described in Example 1) is treated with 1M borane in tetrahydrofuran as described in Example 1.

Sources & evidence

ORD record
ord-b4e380380820459f9fcbb03c786a50fe
Source dataset
uspto-grants-1976_03
Patent number
US03947408

Reaction notes

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