Borane → HCID 54110954, compound

HRID 268177Notes

Reaction equation

HRID 268177 reaction equation
[NH:1]1[CH2:8][CH2:7][CH2:6][C@H:2]1[C:3]([OH:5])=O.[CH2:9]([O:16][C:17]1[CH:29]=[C:21]2[C:22](O[C:25](=O)[N:26](C)[C:20]2=[CH:19][CH:18]=1)=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.B>O1CCCC1>[CH2:9]([O:16][C:17]1[CH:18]=[CH:19][C:20]2[N:26]([CH3:25])[C:3](=[O:5])[CH:2]3[CH2:6][CH2:7][CH2:8][N:1]3[CH2:22][C:21]=2[CH:29]=1)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

5

Reactant 3

HCID 6331BoraneHCID 145742L-ProlineHCID 54431203HCID 54431203, compound

Product 1

HCID 54110954HCID 54110954, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The above compound is obtained when 7-benzyloxy- 1,2,3,11a-tetrahydro-10-methyl-5H-pyrrolo[2,1-c] [1,4]benzodiazepin- 5,11(10H)-dione (prepared from proline and 5-benzyloxy-N-methylisatoic anhydride by the procedure of Example 1) is treated with 1 M borane in tetrahydrofuran by the procedures of Example 1.

Sources & evidence

ORD record
ord-841e04713eb646c188017fc1c324b230
Source dataset
uspto-grants-1976_03
Patent number
US03947408

Reaction notes

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