HRID26819

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID260

Hydrogen Bromide

BrH

HCID9082

Cysteamine hydrochloride

C2H8ClNS

HCID3084707

4-Methylimidazol-5-ylmethanolhydrochloride

C5H9ClN2O

PRODUCTS

生成物

HCID178419247

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

A mixture of 4-hydroxymethyl-5-methylimidazole hydrochloride (15.0 g.), cysteamine hydrochloride (11.5 g.) and a solution of hydrogen bromide in acetic acid (48%, 225 ml.) was heated under reflux for 7 hours. Cooling afforded 4-methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrobromide (21.6 g.), m.p. 208°-211°.

WORKUP

后处理

temperatureunder reflux for 7 hours
temperatureCooling