Ammonium Hydroxide → HCID 178446949, compound

HRID 268280Notes

Reaction equation

HRID 268280 reaction equation
[ClH:1].[CH2:2]([O:7][C:8]1[CH:9]=[C:10]([CH:12]=[CH:13][C:14]=1[O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[NH2:11])[CH2:3][CH2:4][CH2:5][CH3:6].[NH4+].[OH-].Cl.N([C:31]1[C:40]2[C:35](=[CH:36][CH:37]=[C:38]3[N:43]=[CH:42][NH:41][C:39]3=2)[N:34]=[C:33]([CH3:44])[CH:32]=1)C1C=CC=CC=1>C(O)C>[ClH:1].[CH2:2]([O:7][C:8]1[CH:9]=[C:10]([CH:12]=[CH:13][C:14]=1[O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[NH:11][C:31]1[C:40]2[C:35](=[CH:36][CH:37]=[C:38]3[N:43]=[CH:42][NH:41][C:39]3=2)[N:34]=[C:33]([CH3:44])[CH:32]=1)[CH2:3][CH2:4][CH2:5][CH3:6]

Participants

5

Reactant 3

HCID 14923Ammonium HydroxideHCID 21551527HCID 21551527, compoundHCID 178428198HCID 178428198, compound

Product 1

HCID 178446949HCID 178446949, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ten grams (0.033 m.) of 3,4-dipentoxyaniline hydrochloride was dissolved in 500 ml. of ethanol, then neutralized with 28% NH4OH. After adding 7.2 g. (0.033 m.) of the compound of Example I, C., the mixture was refluxed with stirring overnight. Concentration in vacuo gave 17 g. The crude product was recrystallized from 300 ml. of MeOH to yield 16 g. m.p. 236°-238°C.

Workup

  1. additionAfter adding 7.2 g
  2. temperature, the mixture was refluxed
  3. concentrationConcentration in vacuo
  4. customgave 17 g
  5. customThe crude product was recrystallized from 300 ml
  6. customof MeOH to yield 16 g

Sources & evidence

ORD record
ord-9ca312691d5d414c8f86b5cfb42892fd
Source dataset
uspto-grants-1976_03
Patent number
US03947434

Reaction notes

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