反应详情

In a one liter three-necked reaction flask equipped with a water-separator device (Dean-Stark) and a reflux condenser there are added 700 ml. of benzene, 54 g (0.5 mol) of 1,3-propanedithiol 46 g (0.5 mol) of monohydrated glyoxylic acid and 0.5 g (2.9 mmol) toluene-p-sulfonic acid. The mixture is heated to reflux with stirring. After 18 ml. (1 mol) water has been condensed, the hot solution is decanted from the precipitate formed on the container walls. The solvent is evaporated under reduced pressure and the residue is crystallized from toluene to yield 1,3-dithiane-2-carboxylic acid.

1. additionthere are added 700 ml
2. temperatureThe mixture is heated
3. temperatureto reflux
4. customcondensed
5. customthe hot solution is decanted from the precipitate
6. customformed on the container walls
7. customThe solvent is evaporated under reduced pressure
8. customthe residue is crystallized from toluene