反应详情

A mixture of 3.0 g. (9.5 mmol.) of 3-(4-hydroxybenzoyl)-2-phenylbenzofuran, 6.2 g. (0.029 mol.) of 1,4-dibromobutane and 3.9 g. (0.029 mol.) of potassium carbonate in 100 ml. of dry acetone is refluxed for 18 hours. The reaction mixture is cooled, filtered and the filtrate is concentrated under reduced pressure then heated on a steam bath in vacuo to remove excess 1,4-dibromobutane and leave 3-[4-(4-bromobutoxy)benzoyl]-2-phenylbenzofuran as a residue.

1. additionA mixture of 3.0 g
2. temperatureThe reaction mixture is cooled
3. filtrationfiltered
4. concentrationthe filtrate is concentrated under reduced pressure
5. temperaturethen heated on a steam bath in vacuo
6. customto remove excess 1,4-dibromobutane