Hydrochloric Acid → 4-[2-(Diethylamino)ethoxy]benzoic acid hydrochloride

HRID 268348Notes

Reaction equation

[ClH:1].[CH2:2]([N:4]([CH2:19][CH3:20])[CH2:5][CH2:6][O:7][C:8]1[CH:18]=[CH:17][C:11]([C:12]([O:14]CC)=[O:13])=[CH:10][CH:9]=1)[CH3:3].Cl>>[ClH:1].[CH2:19]([N:4]([CH2:2][CH3:3])[CH2:5][CH2:6][O:7][C:8]1[CH:9]=[CH:10][C:11]([C:12]([OH:14])=[O:13])=[CH:17][CH:18]=1)[CH3:20]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 21435382Ethyl 4-(2-diethylaminoethoxy)benzoate hydrochloride

Product 1

HCID 429374924-[2-(Diethylamino)ethoxy]benzoic acid hydrochloride

Procedure

Hydrolysis of ethyl 4-(2-diethylaminoethoxy)benzoate hydrochloride with aqueous concentrated hydrochloric acid at 100° for two hours gives 4-(2-diethylaminoethoxy)benzoic acid hydrochloride, m.p. 166°-168°.

Sources & evidence

ORD record: ord-42c388ce002945c88a8d35f0b9bf3f25
Source dataset: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03947470

Reaction notes

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