Methylamine → 3-[4-(4-Methylaminobutoxy)benzoyl]-2-phenylbenzofuran
Reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:29]=[CH:28][C:10]([C:11]([C:13]2[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=3[O:15][C:14]=2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:12])=[CH:9][CH:8]=1.[CH3:30][NH2:31]>>[CH3:30][NH:31][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:29]=[CH:28][C:10]([C:11]([C:13]2[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=3[O:15][C:14]=2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[O:12])=[CH:9][CH:8]=1Participants
3
Procedure
Reaction of 3-[4-(4-bromobutoxy)benzoyl]-2-phenylbenzofuran with methylamine according to the procedure described in Example 4 gives 3-[4-(4-methylaminobutoxy)benzoyl]-2-phenylbenzofuran.
Sources & evidence
- ORD record
- ord-3c566276d8734805bf73d3e0b1a4ad57
- Source dataset
- uspto-grants-1976_03
- Patent number
- US03947470
Reaction notes
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