反应详情

4-(2-methylthiophenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine from 1-(5,6,7,8-tetrahydronaphth-1-yloxy)-3-bromopropane and 1-(2-methylthiophenyl)-piperazine; yield 64% of theory; m.p. of the hydrochloride 224°-225°C. decomp.); 4-(3-trifluoromethylphenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine from 1-(5,6,7,8-tetrahydro-napth-1-yloxy)-3-bromopropane and 1-(3-trifluoromethylphenyl)-piperazine; yield 84% of theory; m.p. of the dihydrochloride: 182°-183°C.

1. custom182°-183°C.