Acetic Acid → HCID 21413811, compound

HRID 268503Notes

Reaction equation

HRID 268503 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[C:10]1[CH:20]=[CH:19][C:13]([C:14](=[CH2:18])[C:15](N)=[O:16])=[CH:12][CH:11]=1.Cl.C(O)(=[O:24])C>>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[C:10]1[CH:20]=[CH:19][C:13]([C:14](=[CH2:18])[C:15]([OH:24])=[O:16])=[CH:12][CH:11]=1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 21413821HCID 21413821, compound

Product 1

HCID 21413811HCID 21413811, compound

Procedure

A mixture of 0.01 mole of p-(benzoxazol-2-yl)-atropamide, 15 ml. of acetic acid and 15 ml. of concentrated hydrochloric acid is heated on the steam-bath for 1 hour. Filtration of the reaction mixture into 200 ml. of cold water, followed by filtration of the resulting precipitate, gives p-(benzoxazol-2-yl)atropic acid.

Workup

  1. filtrationFiltration of the reaction mixture into 200 ml
  2. filtrationof cold water, followed by filtration of the resulting precipitate

Sources & evidence

ORD record
ord-9245224f3ec149e7aba239208abfaab5
Source dataset
uspto-grants-1976_03
Patent number
US03947582

Reaction notes

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