HRID268507

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8433

1,3-Diphenyl-1,3-propanedione

C15H12O2

2 次

HCID8868

Ethyl acetoacetate

C6H10O3

HCID11204

Acetyl fluoride

C2H3FO

2 次

HCID67999

Benzoyl fluoride

C7H5FO

HCID69136

Ethyl 2-oxocyclopentanecarboxylate

C8H12O3

HCID69949

3-Methyl-2,4-pentanedione

C6H10O2

HCID79063

Ethyl 2-acetylacetoacetate

C8H12O4

HCID12131181

2,4-Pentanedione, 3-acetyl-3-methyl-

C8H12O3

HCID21438948

未命名化合物

PRODUCTS

生成物

结构：O=C(c1ccccc1)C(C(=O)c1ccccc1)C(=O)c1ccccc1

HCID413869

TRIBENZOYLMETHANE

C22H16O3

HCID786313

未命名化合物

PROCEDURE

实验过程

When the thallous salts of ethyl acetoacetate, 2-carbethoxycyclopentanone, and 3-methylpentane-2,4-dione, prepared according to Example 1, are treated with acetyl fluoride at room temperature as described in Example 4, ethyl 2-acetyl-acetoacetate, 2-acetyl-2-carbethoxycyclopentanone, and 3-acetyl-3-methylpentane-2,4-dione, respectively, are obtained in 95% yield. Tribenzoylmethane is prepared by treating the thallous salt of dibenzoylmethane with benzoyl fluoride in the same manner. Acetyldibenzoylmethane is prepared by treating the thallous salt of dibenzoylmethane with acetyl fluoride.

WORKUP

后处理

customrespectively, are obtained in 95% yield

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9f27d11f015549b89859d82d99f296af
来源数据集: uspto-grants-1976_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US03947488
来源说明: uspto-grants-1976_03

反应 SMILES

[C:1]([O:7]CC)(=O)[CH2:2][C:3]([CH3:5])=[O:4].[C:10]([CH:15]1[CH2:19][CH2:18][CH2:17][C:16]1=[O:20])(OCC)=O.C[CH:22]([C:26](=O)[CH3:27])[C:23](=O)[CH3:24].[C:29](F)(=O)C.[C:33]([CH:36]([C:42]([CH3:44])=O)C(OCC)=O)(=O)[CH3:34].[C:45]([C:48]1([C:54](OCC)=O)[CH2:52][CH2:51][CH2:50][C:49]1=O)(=[O:47])[CH3:46].C(C(C)(C(=O)C)C(=O)C)(=O)C.C(CC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.C(F)(=O)C1C=CC=CC=1>>[C:16]([CH:2]([C:1](=[O:7])[C:49]1[CH:50]=[CH:51][CH:52]=[CH:48][CH:54]=1)[C:3](=[O:4])[C:5]1[CH:27]=[CH:26][CH:22]=[CH:23][CH:24]=1)(=[O:20])[C:15]1[CH:10]=[CH:29][CH:17]=[CH:18][CH:19]=1.[C:45]([CH:2]([C:1](=[O:7])[C:10]1[CH:15]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:3](=[O:4])[C:5]1[CH:44]=[CH:42][CH:36]=[CH:33][CH:34]=1)(=[O:47])[CH3:46]