Hydrochloric Acid → N-Ethyl-3,6-carbazolediol

HRID 268518Notes

Reaction equation

HRID 268518 reaction equation
O.[OH-].[Na+].C([O:7][C:8]1[CH:9]=[CH:10][C:11]2[N:12]([CH2:25][CH3:26])[C:13]3[C:18]([C:19]=2[CH:20]=1)=[CH:17][C:16]([O:21]C(=O)C)=[CH:15][CH:14]=3)(=O)C.Cl>>[CH2:25]([N:12]1[C:13]2[CH:14]=[CH:15][C:16]([OH:21])=[CH:17][C:18]=2[C:19]2[C:11]1=[CH:10][CH:9]=[C:8]([OH:7])[CH:20]=2)[CH3:26]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 14798Sodium HydroxideHCID 12331788N-ethyl-3,6-carbazolediol diacetate

Product 1

HCID 21419583N-Ethyl-3,6-carbazolediol

Procedure

To 700 ml of water containing 80 g (2.0 mole) of sodium hydroxide is added 85 g (0.27 mole) of N-ethyl-3,6-carbazolediol diacetate. The reaction mixture is heated for one hour then acidified with 3N hydrochloric acid to give N-ethyl-3,6-carbazolediol which is recrystallized from ethanol-water. M.P. 190°-200°C (dec.).

Workup

  1. temperatureThe reaction mixture is heated for one hour

Sources & evidence

ORD record
ord-8c33ea2c860d4611ab818399c31549e7
Source dataset
uspto-grants-1976_03
Patent number
US03947593

Reaction notes

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