Ethanol → 675617-98-8

HRID 268598Notes

Reaction equation

HRID 268598 reaction equation
[CH2:1]([N:3]1[C:7]([CH:8]=[N:9][OH:10])=[N:6][CH:5]=[N:4]1)[CH3:2].[CH2:11]([OH:13])[CH3:12]>[OH-].[OH-].[Pd+2]>[C:11]([O-:10])(=[O:13])[CH3:12].[CH2:1]([N:3]1[C:7]([CH2:8][NH3+:9])=[N:6][CH:5]=[N:4]1)[CH3:2]

Participants

4

Reactant 2

HCID 702EthanolHCID 136335088HCID 136335088, compound

Product 1

HCID 86603337675617-98-8

Reagents, catalysts & solvents 1

HCID 9942167Palladium hydroxideCatalyst

Procedure

A mixture of 1-ethyl-1H-1,2,4-triazole-5-carbaldehyde oxime (6.17 g, 44 mmol), 10% palladium hydroxide on carbon (2.9 g) acetic acid (125 mL) and ethanol (125 mL) were stirred under an atmosphere of hydrogen for 14 hours. The reaction mixture was filtered and concentrated in vacuo to give the title compound (7.7 g) 1H-NMR (d6-DMSO) δ 1.32 (3H, t, J=7 Hz), 1.89 (3H, s), 3.89 (2H, br), 4.17 (2H, q, J=7 Hz), 7.80 (1H, s).

Workup

  1. filtrationThe reaction mixture was filtered
  2. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-bab6cf9741d448c0be083d102f1aedc7
Source dataset
uspto-grants-2008_11
Patent number
US07446117B2

Reaction notes

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