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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268656Generated: October 28, 2026

2-Fluoro-4-biphenylboronic Acid → 2-[1-Ethyl-8-(2-fluoro-biphenyl-4-YL)-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-B]indol-1-YL]-ethanol

https://huagongshe.com/reaction/268656

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-biphenylboronic AcidHCID 2774698—
Reactant2-(8-Bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanolHCID 69196696—
Product2-[1-Ethyl-8-(2-fluoro-biphenyl-4-YL)-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-B]indol-1-YL]-ethanolHCID 11396960—

Reaction Steps

The title compound is prepared in a manner analogous to Example 1, except using 2-(8-bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanol and 2-fluorobiphenyl-4-boronic acid in step 1.F.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446122B2
Source datasetuspto-grants-2008_11
ORD IDord-9a035ebbe7cf4894a882316a581b9c67
Source noteuspto-grants-2008_11