HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68968162, compound → HCID 17986293, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68968162 | HCID 68968162 | — |
| Solvent | Thionyl Chloride | HCID 24386 | — |
| Product | HCID 17986293 | HCID 17986293 | 189.5% |
Reaction Steps
2-Chloro-4-(3-piperidin-1-ylpropoxy)benzoic acid hydrochloride (D27) (1.0 g) was heated at reflux in thionyl chloride (20 ml) for 1.5 h. The thionyl chloride was removed by evaporation and the residue evaporated from DCM (3×30 ml) to give the title compound (D28) (1.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446103B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-1656746903af49b4ba3c6862b0fb1892 |
| Source note | uspto-grants-2008_11 |