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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268795Generated: October 27, 2026

5-Bromoindole → 5-Bromo-3-cyanoindole

https://huagongshe.com/reaction/268795

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromoindoleHCID 24905—
Reactant4-Bromo-1H-indole-3-carbonitrileHCID 2763232—
Product5-Bromo-3-cyanoindoleHCID 362335466%

Reaction Steps

5-Bromo-1H-indole-3-carbonitrile LXII (3.72 g, 66% yield) was prepared from 5-bromo-indole using the procedure described for 4-bromo-1H-indole-3-carbonitrile LVII (see Example 14).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-5ae5ea2dc3824f19a048b99f71002442
Source noteuspto-grants-2008_11