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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268839Generated: October 25, 2026

3-(1H-Indol-6-yl)-3-pyridin-3-yl-acrylic acid ethyl ester → 3-(1H-Indol-6-yl)-3-pyridin-3-yl-propionic acid ethyl ester

https://huagongshe.com/reaction/268839

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(1H-Indol-6-yl)-3-pyridin-3-yl-acrylic acid ethyl esterHCID 67355924—
Reactant3-(3-cyano-1H-Indol-4-yl)-3-phenyl-propionic acid ethyl esterHCID 67356038—
Product3-(1H-Indol-6-yl)-3-pyridin-3-yl-propionic acid ethyl esterHCID 59831693—

Reaction Steps

3-(1H-Indol-6-yl)-3-pyridin-3-yl-propionic acid ethyl ester CLVIII was prepared from 3-(1H-indol-6-yl)-3-pyridin-3-yl-acrylic acid ethyl ester using the procedure described above for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-propionic acid ethyl ester LIX (Example 14).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-7bee7d0d62b5436b8f83d9ebbca89ea1
Source noteuspto-grants-2008_11