Trifluoroacetic acid → HCID 59831680, compound

HRID 268868Notes

Reaction equation

HRID 268868 reaction equation
FC(F)(F)C([O-])=O.[CH3:8][O:9][C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH:19]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[CH2:20][C:21]([NH:23][CH3:24])=O)[CH:17]=2)[NH:12][N:11]=1.FC(F)(F)C(O)=O.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[CH3:8][O:9][C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH:19]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[CH2:20][CH2:21][NH:23][CH3:24])[CH:17]=2)[NH:12][N:11]=1

Participants

5

Reactant 4

HCID 6422Trifluoroacetic acidHCID 84468TrifluoroacetateHCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 67356537HCID 67356537, compound

Product 1

HCID 59831680HCID 59831680, compound

Procedure

[3-(3-Methoxy-1H-indazol-5-yl)-3-phenyl-propyl]-methyl-amine CCXIII was prepared as a trifluoroacetate from 3-(3-methoxy-1H-indazol-5-yl)-N-methyl-3-phenyl-propionamide and trifluoroacetic acid using the procedure described for preparation of [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (Example 4). MS (M+H)=297.

Sources & evidence

ORD record
ord-4174a530033d4050b3ab79b49bb71ce2
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

Loading…