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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 268872Generated: November 1, 2026

3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester → 3-(3-methyl-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester

https://huagongshe.com/reaction/268872

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterHCID 67355322—
ReactantHCID 178434225HCID 178434225—
Product3-(3-methyl-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl esterHCID 178470868—

Reaction Steps

3-(3-Methyl-1H-indazol-5-yl)-3-phenyl-acrylic acid ethyl ester CCXIX) was prepared from 3-methyl-5-bromo-1H-indazole using the procedure described for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl ester LVIII (Example 14).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446118B2
Source datasetuspto-grants-2008_11
ORD IDord-2ecaf6b4fb2e403b85b3e5b25f1f085e
Source noteuspto-grants-2008_11