Trifluoroacetic acid → HCID 59831620, compound

HRID 268895Notes

Reaction equation

HRID 268895 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[CH:10]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:11][C:12]([NH:14][CH3:15])=O)[CH:3]=[N:2]1.C(O)(C(F)(F)F)=O.N1C2C(=CC=CC=2C(C2C=CC=CC=2)CCNC)C=C1>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[CH:10]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:11][CH2:12][NH:14][CH3:15])[CH:3]=[N:2]1

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 17747555[3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amineHCID 67356682HCID 67356682, compound

Product 1

HCID 59831620HCID 59831620, compound

Procedure

[3-(1H-Indazol-7-yl)-3-phenyl-propyl]-methyl-amine CCLX was prepared from 3-(1H-indazol-7-yl)-N-methyl-3-phenyl-propionamide and TFA using the procedure described for preparation of [3-(1H-Indol-7-yl)-3-phenyl-propyl]-methyl-amine XX (Example 4).

Sources & evidence

ORD record
ord-91aa4543a41642b6be754d6ec6fda0f9
Source dataset
uspto-grants-2008_11
Patent number
US07446118B2

Reaction notes

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