HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1-propanol → 3-bromo-N-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Reactant | m-Bromobenzenesulphonyl chloride | HCID 17943 | — |
| Product | 3-bromo-N-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide | HCID 43501900 | 89% |
Reaction Steps
Prepared by general procedure III from 2-amino-2-methyl-1-propanol (8.91 g, 100 mmol) and commercially available 3-bromobenzenesulfonyl chloride (2.88 mL, 20 mmol) to give the title compound as a white solid (5.47 g, 89%). MS (ISN) 306.1 [(M−H)−], 308.2 [(M+2−H)−]. mp 138° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446113B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-15960db67a934c89948ef5d564e0109c |
| Source note | uspto-grants-2008_11 |