Ethanolamine → HCID 43501995, compound

HRID 268941Notes

Reaction equation

HRID 268941 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:12])=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:7]=1.[CH2:13]([CH2:15][NH2:16])[OH:14]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:12])=[C:6]([S:8]([NH:16][CH2:15][CH2:13][OH:14])(=[O:10])=[O:9])[CH:7]=1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 49621635-Bromo-2-methylbenzene-1-sulfonyl chloride

Product 1

HCID 43501995HCID 43501995, compoundYield 58%

Procedure

Prepared by general procedure III from 5-Bromo-2-methyl-benzenesulfonyl chloride (1.6 g, 6 mmol, synthesized according to J. Am. Chem. Soc., 1940, 62, 511-514) and ethanolamine (1.0 mL, 17 mmol) to give the title compound (1.02 g, 58%) as a pale-yellow solid. MS (ISP) 294.1[(M+H)+], 296.2[(M+2+H)+].

Sources & evidence

ORD record
ord-fed2ce371bb1420398239d704e0e7461
Source dataset
uspto-grants-2008_11
Patent number
US07446113B2

Reaction notes

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