Ammonium Hydroxide → 5-bromo-2-methylbenzenesulfonamide

HRID 268942Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:12])=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:7]=1.[OH-].[NH4+:14]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:12])=[C:6]([S:8]([NH2:14])(=[O:10])=[O:9])[CH:7]=1

Participants

Reactant 2

HCID 14923Ammonium Hydroxide

HCID 49621635-Bromo-2-methylbenzene-1-sulfonyl chloride

Product 1

HCID 24468215-bromo-2-methylbenzenesulfonamideYield 55%

Procedure

Prepared by general procedure III from 5-Bromo-2-methyl-benzenesulfonyl chloride (1.89 g, 7 mmol) and ammonium hydroxide (20 mL) to give the title compound (0.96 g, 55%) as a white solid. MS (ISN) 248.0[(M−H)−], 250.0[(M+2−H)−].

Sources & evidence

ORD record: ord-a6984775821f433d9d3d6de62b3e360c
Source dataset: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07446113B2

Reaction notes

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